Hypertension is a common accompaniment of type 2 diabetes and sets in the course of type 1 diabetes. Hypertension magnifies many fold the damage to the target organs (kidneys, heart, eyes etc) in diabetics and hence needs significant attention. Drug treatment in addition to lifestyle intervention is recommended to reach the prescribed goals by ADA and AHA (BP< 130/85 mm of Hg). Various drug trials on hypertensive diabetics are Appropriate Blood Pressure Control in Diabetes (ABCD), Fosinopril vs. Amlodipine Cardiovascular Events Randomized Trial (FACET), Irbesartan Diabetic Nephropathy Trial (IDNT). In perspective because of their efficacy, lesser side effects and good metabolic profile, ACE inhibitors rank as first-line treatment in both type 1 and type 2 diabetes.
0 comments:
Post a Comment